The implantation process of a good-quality embryo may even fail if the uterus and endometrial conditions aren’t right. Good quality of the embryo is indeed the most essential part of an IVF cycle but it is also essential to transfer it into the uterus when it is ready to receive it with high endometrial receptivity.
If the embryo is transferred during the window of implantation period, then the chances of a successful pregnancy will increase. You can consult an experienced IVF doctor to avail of appropriate infertility treatments in Siliguri. The doctor may also refer you to an Endometrial Receptivity Array (ERA) test to evaluate the best time for transferring the embryo based on your endometrial receptivity.
Purpose Of ERA Test
- The main purpose of the ERA diagnostic tool is to determine the key reason behind recurrent pregnancy loss and IVF implantation failure. The role of the uterine lining in such failures is mainly evaluated by ERA.
- Another purpose of the test is to maximize the chances of pregnancy by understanding the best time for embryo transfer.
- This method also helps in saving good embryos because the success rates of pregnancy increase when a personalized way of embryo transfer is followed. The effectiveness of personalized embryo transfer is much higher than the traditional method of frozen embryo transfer.
- Additionally, another key role of this diagnostic test is to categorize the endometrium as a pre-receptive, early receptive, receptive, late receptive, and post-receptive phase. These phases help in determining that the endometrium is in the before, near, or closing phase of the window of implantation.
- ERA test precisely detects the receptive phase, where the endometrium is in the best state for implantation. This perfect quantity of progesterone exposure is also received during this period, which also contributes to a successful pregnancy.
Procedure Of ERA Test
- The doctor will first prescribe you estrogens pills to make the estrogens levels proper and the uterus lining 7mm. Additionally, progesterone pills will also be prescribed for 5-6 days to make the endometrium receptive. This procedure is similar to the preparation of a normal frozen embryo transfer.
- An endometrial autopsy will be performed when the window of implantation phase is expected. During this biopsy, a pipelle will be inserted into the vagina, which may feel discomfort for some patients. Using this small instrument, the uterine lining will be scratched to obtain some tissue from the lining.
- This sample will be then sent to the lab for molecular analysis and the best time for implantation will be determined. Almost 200 genes and progesterone exposure length will be analyzed to detect the appropriate implantation time.
- After getting the results of the test, the doctor may reschedule the period of embryo transfer if the result indicates the pre-receptive or post-receptive phase. The initially fixed time for the transfer will be followed if the result indicates a receptive period.
This medical advancement is proven to help you enjoy the phase of parenthood despite several reproductive issues. Hence, without any hesitation, you must contact an expert so that they can recommend you the best infertility treatments in Siliguri. You must remember the fact that these procedures of the ERA test begin 1 month before the scheduled frozen embryo transfer for precise results.